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Cholesterol
Pyrrole disorder, mood + its relation to DNA dysfunction

Pyrroles + our mood: How pyrroles can be traced back to genetics and an experience of anger/rage.

People who suffer pyrrole disorder can present with some of the following symptoms;

Mood/ anger issues/short temper

Skin issues such as acne

Poor dream recall due to a low B6

A family of mostly female siblings

Lack of appetite in the mornings

Pale skin which burns easily in the sun (Lack of zinc for sun protection)

White marks on the nails (Zinc deficiency)

Low immune system

Blood pressure too high (Sometimes too low)



Pyrrole’s are a chemical compound also known as hydroxyhaemopyrrolin-2-one (HPL).


When an individual is diagnosed with a pyrrole disorder it means that the person is excreting excessive amounts of pyrroles(HPL) through their urine.


(Note: It is difficult to test for excess pyrroles via urine as the HPL compound is very light sensitive and degenerates within a short amount of time).


As pyrroles leave the body in an individual who suffers Pyrroluria,   the chemical structure binds and also excretes a large amount of B6 and zinc which can then leave the body with depleted levels.


Emotional stress can increase the amount of pyrroles leaving the body.


The root cause of this most often a genetic issue because the gene is working too fast.

The gene which functions incorrectly is called CBS (Cystathione beta-synthase).


Through my clinical experience I have seen that most individuals with a mutation with the CBS gene have a family member in their lineage with deep anger which they have experience on a chronic level.

The anger is often suppressed. It is note-able how blood pressure is affected on offspring after such an occurrence which we often link to intense times of stress.


Healing an individual who has a polymorphism on this gene (CBS)  is approached through nutraceutical support however I also encourage spiritual, energetic work to accompany such DNA healing to fully allow the body to be supported.

For further reading, please have a read of the article below which discusses ancestral trauma and how it is expressed through changes in our DNA.

Review: The Effects of Trauma, with or without PTSD, on the Transgenerational DNA Methylation Alterations in Human Offspring
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Review: The Effects of Trauma, with or without PTSD, on the Transgenerational DNA Methylation Alterations in Human Offspring

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Pyrrole disorder, mood + its relation to DNA dysfunction

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